Alberto Bosque-Pardos

In vitro drug treatment to proliferate and activate effector cells for immunotherapy

018-063-bosque – STAT5 SUMOylation inhibition increases CD4 and CD8 T-cell proliferation and and production of immune effector molecules in CD8 T-cells and NK (natural killer) cells. Both attributes address critical limiting factors in applying cell therapies to fighting cancers and pathogens. The difficulty of obtaining enough activated effector cells limits the efficacy of cell therapies. In vitro drug... Read More