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Illustration of micro-wells transforming into micro-grooves over time at 37°C.

4D-Printed Programmable Culture Substrate for Controlling Neural Stem Cell Growth

020-006-zhang – Neural stem cells (NSCs) exhibit great promise for treating neurodegenerative diseases and injuries. Treatments will rely on efficient proliferation and differentiation of NSCs into neurons with therapeutic characteristics. Static 2D and 3D microenvironment culture substrates fail to cater to the dynamic cell needs, resulting in sub-optimal, inefficient and uncontrolled differentiation of... Read More

Cisplatin resistant ovarian cancer tumor growth is slowed when treated with DHS. The combination of DHS and Cisplatin proves even more effective, highlighting the re-sensitization of the cancer cells to Cisplatin.

And-1 Inhibition by DHS for Cancer Treatment

017-039-zhu – GW researchers developed DHS (4,4’-trans-dihydroxystilbene) as a new cytotoxic anticancer drug for use alone or in combination with other chemotherapies. Drug toxicity and drug resistance limit the ability of many cytotoxic cancer drugs to effectively treat cancer, a problem which is overcome by DHS. The cancer killing efficacy of DHS is 10-times better than its parent compound, resveratrol,... Read More

(Technology Bundle) Stem cells with transiently reduced p53 to treat diabetes associated kidney disease and peripheral vascular disease

018-044-sen-019-54-sen – Local delivery of endothelial progenitor cells (EPCs) may treat diabetic-related kidney disease (DKD) and peripheral vascular disease (PVD). EPCs may be obtained from a patient’s peripheral blood. The hyperglycemic state in diabetic patients causes transplanted EPCs to undergo apoptosis, creating a challenge for such therapies. By transiently silencing the apoptotic gene p53, Dr. Sen’s... Read More

PASSIVE RAM-AIR INERTIAL STABILISATION MECHANISM

020-001-waldron – Students at the George Washington University are developing a passive stabilization mechanism for atmospheric rocket flight which extracts work from oncoming air to generate a restoring force. Airflow channeled through a turbine section spins a shaft, which exerts a torque proportional to its speed and perpendicular to the rocket’s trajectory. This additional stability allows for a... Read More

CMOS Compatible Light Emitting Tunnel Junction for Photonic Integrated Circuits (PIC) and Optical Communication

019-055-sorger – With the emergence of photonic integration, the challenges (a) to create light from silicon and (b) to realize electronically compact photonics have delayed the anticipated introduction of photonics into electronic consumer products. While a variety of light emitters exist such as LEDs and semiconductor solid-sate-lasers, existing technology is hindered by: specialized and costly materials... Read More

golf ball on work bench and graphs shoing ball speed and distance

NEXT GENERATION OF GOLF BALL DESIGN

018-023-balaras – Researchers at the George Washington University and Arizona State University have been developing a family of novel golf ball designs that can reduce drag by as much as 15% compared to traditional designs based on dimples. The new designs will allow for improved aerodynamics performance which can be used to increase the distance the ball travels or to improve the feel of the ball. Dimples... Read More

PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids

019-027-deghanian – Researchers at The George Washington University are developing innovative analytics for power grid online surveillance (event detection and classification with minimum latency) and real-time situational awareness. The novel analytics can be deployed as a stand-alone next-generation smart sensor or can be embedded within the existing phasor measurement units (PMUs) and intelligent... Read More

COTSKNIGHT: Practical Defense against Cache Timing Channel Attacks using Cache Monitoring and Partitioning Techniques

019-034-venkataramani – Researchers at GW are developing COTSKnight, a novel framework that offers a holistic infrastructure for both detecting and defending against cache-based timing channels. Cache timing channels endangered shared computer system by stealing information without leaving physical traces in shared cache. COTSKnight repurposes the performance monitoring tool and detect various protocols of cache... Read More

EZ-PASS: An Energy & Performance-Efficient Power-gating Router Architecture for Scalable NoCs

019-060-louri-ezpass – Researchers at The George Washington University are developing an innovative method to design a performance and power-efficient network-on-chip for the parallel computing chips. The novel network-on-chip design invented at GW will significantly improve performance and power efficiency of parallel computing chips. Considering that the innovation can be applied to any multicore systems and... Read More

Learning-Based High-performance, Energy-Efficient, Fault-Tolerant On-Chip Communication Design Framework

019-061-louri-noc – Researchers at The George Washington University are developing an innovative method to tackle the major challenges in on-chip communication: performance scaling, energy-efficiency, and reliability. The novel network-on-chip technology invented at GW will significantly improve performance, power, and reliability simultaneously. Considering that the innovation can be applied to any current and... Read More

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