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Hardware-Software Cooperative Approach to Fine-grained Energy Profiling in Applications

014-051-venkataramani – With the exponential increase in computational performance and widespread use of computers, energy costs incurred by software applications have also grown rapidly.  Therefore, it is increasingly important for developers to accurately estimate the energy consumption profile of software in order to develop energy-efficient software. However, conventional measures of software energy efficiency... Read More

Molten Electrolyte Rechargeable Air Battery

013-023-licht – Researchers at The George Washington University have developed a new class of battery, which uses a molten electrolyte, and has amongst the highest intrinsic electric energy storage capacities, of any class of batteries and is rechargeable.  In the past, researchers were able to produce very high capacity batteries (e.g. VB batteries) lacking recharge capabilities or rechargeable molten... Read More

Powerful Predictive Software for Sudden Critical Events

014-049-zeng-2 – Critical transitions are macroscopic systemic changes that are comprised of a large number of microscopic elements.  Sudden onset of critical transitions such as stock market crashes and rapid deterioration of complex diseases are difficult to forecast using data analysis. GW Researchers developed an algorithm that analyzes time series data to identify key groups of variables that can... Read More

Early Detection of Complex Diseases: Software Finds Hidden Signals in Time Series Data

014-049-zeng – GW researchers developed software to identify early signals of critical transition events using time series microarray data.  The tools can be applied to identify tell-tale signs of disease onset that otherwise would seem insignificant. For diseases with acute onset of symptoms, early detection and timely intervention may be necessary for favorable clinical outcomes. Time series... Read More

STEP Cement: Cost Competitive, Zero Carbon Dioxide Emission Process for the Production of Cement

012-010-licht – The production of cement is an energy intensive industrial process that accounts for an estimated 5-6% of all human-generated carbon dioxide (CO) emissions.  Society consumes over 3x10 kg of cement annually and the cement industry releases 9 kg of CO for each 10 kg of cement produced.  The majority of the CO is released from the conversion of limestone (CaCO) to lime CaO, but another 30-40%... Read More

Kinase inhibition to prevent latent HIV reservoir

014-048-tyagi – The invention is a novel therapeutic approach which combines DNA dependent protein kinase (DNA-PK) inhibitors with highly active anti-retroviral therapy (HAART) regimen to efficiently restrict the replication of HIV viruses. HAART by itself fails to eradicate HIV because of its inability to kill latent and transcriptionally silent proviruses. These viruses, stored in latent reservoirs,... Read More

Ultrasound Stimulation of Insulin Release from Pancreatic Beta Cells

014-038-zderic – According to statistics released by the American Diabetes Association about 26 million Americans have diabetes.  The staggering numbers tell us why it is so important to establish new methods to treat and manage diabetes. Current therapies for management of diabetes demand significant life style changes. Many patients comply poorly with the pharmacological treatment which involves... Read More

Next Generation Diagnostics: pathogen detection from metagenomic data

014-053-crandall – Pathoscope 2.0 is a comprehensive software that uses Bayesian statistics to rapidly identify pathogens from next-generation sequencing (NGS) data of complex biological and environmental samples. The software maps NGS reads to a huge reference database of pathogens (including fungal, viral, bacterial, and parasite genomes), also created by the inventors, and reports back pathogen identity,... Read More

Proto-type layout from computer simulation

High Sensitivity CMOS Portable Chip With Increased Functionalized Surface Area

014-031-goktas – A researcher at George Washington University has developed a new CMOS chip with a novel circuit configuration, by replacing the traditional cantilever structure with a beam structure in a MEMS device. The unique design creates a 300-400% increase over the normal 20% functionalized area for a single device. Typically bio-sensors use optical or mass sensing for high accuracy and precision,... Read More

Antisense RNA therapy for liver carcinoma

014-022-kumar – A GW researcher invented a nucleic acid based therapy for Hepatitis C Virus (HCV) infection associated hepatocellular carcinoma (HCC, liver cancer). Currently available antiviral drugs can only eliminate short term effects of the HCV. But liver damage, caused by chronic HCV infections, carries the very high risk of developing into hepatocellular carcinoma, sometimes even decades after the... Read More

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